What is the main purpose of preimplantation genetic testing (PGT) in IVF?

• A. To screen embryos for chromosomal abnormalities or specific genetic disorders before transfer, reducing miscarriage risk and enabling selection of suitable embryos
• B. Determine best blastocyst stage
• C. Enhance embryo implantation rate via culture conditions
• D. Assess maternal age impact

Answer: (C)

PGT is used to screen embryos created in IVF for chromosomal abnormalities (such as aneuploidy) and for specific genetic disorders before transfer. By identifying embryos with normal chromosome numbers or without known mutations, it helps reduce miscarriage risk and increases the chance of a healthy pregnancy by enabling selection of suitable embryos for transfer. It’s performed on embryos at the blastocyst stage and involves a genetic analysis of a small biopsy, not altering how embryos are cultured or how they’re grown.

The other options don’t describe the purpose of PGT. It isn’t about determining the best blastocyst stage, improving implantation through culture conditions, or directly assessing maternal age impact.