Which genetic consideration is used to improve implantation success and reduce miscarriage risk in infertility treatments?

• A. Maternal blood typing
• B. Sperm motility alone
• C. Embryo screening for aneuploidy
• D. Donor selection criteria

Answer: (C)

Embryo genetic screening for aneuploidy targets the chromosomal makeup of the embryo itself. Many implantation failures and miscarriages in infertility treatments are caused by embryos that have the wrong number of chromosomes (aneuploidy). By testing embryos before transfer and selecting those with the normal number of chromosomes (euploid), clinicians place embryos with the highest likelihood of proper development back into the uterus. This approach directly improves the chance of successful implantation and reduces the risk of miscarriage compared with transferring embryos without regard to chromosomal status.

Other options don’t specifically address embryo chromosome balance: maternal blood type concerns immune or compatibility factors but not embryonic viability; focusing on sperm motility improves fertilization chances but not the chromosomal integrity of the embryo; donor selection criteria can influence genetics indirectly but does not systematically reduce the risk of aneuploidy-related miscarriage in the usual infertility treatment context.