Which of the following is a known adverse effect of clomiphene citrate?

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Multiple Choice

Which of the following is a known adverse effect of clomiphene citrate?

Explanation:
Clomiphene citrate works by blocking estrogen receptors in the hypothalamus, which shifts the hormonal balance to promote ovulation. This disruption of estrogen signaling can lead to several systemic effects, including fluid retention and metabolic changes that some patients experience as weight gain. Among the options, weight gain is a recognized adverse effect associated with this medication. While hot flashes can occur with clomiphene, the other choices—hypertension and hair loss—are not typical adverse effects of this drug.

Clomiphene citrate works by blocking estrogen receptors in the hypothalamus, which shifts the hormonal balance to promote ovulation. This disruption of estrogen signaling can lead to several systemic effects, including fluid retention and metabolic changes that some patients experience as weight gain. Among the options, weight gain is a recognized adverse effect associated with this medication. While hot flashes can occur with clomiphene, the other choices—hypertension and hair loss—are not typical adverse effects of this drug.

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