Which of the following is a preventive strategy for OHSS in IVF cycles?

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Multiple Choice

Which of the following is a preventive strategy for OHSS in IVF cycles?

Explanation:
Preventing OHSS hinges on controlling how the ovaries respond to stimulation. Using a GnRH antagonist protocol achieves this by blocking the premature LH surge during stimulation, which helps limit excessive follicle growth and estrogen rise that contribute to OHSS. Additionally, antagonist cycles allow triggering ovulation with a GnRH agonist instead of hCG; this GnRH agonist trigger markedly lowers the risk and severity of OHSS compared with an hCG trigger. In contrast, high-dose gonadotropins increase OHSS risk, prolonged bed rest has no proven protective effect, and avoiding GnRH antagonists would remove this protective control.

Preventing OHSS hinges on controlling how the ovaries respond to stimulation. Using a GnRH antagonist protocol achieves this by blocking the premature LH surge during stimulation, which helps limit excessive follicle growth and estrogen rise that contribute to OHSS. Additionally, antagonist cycles allow triggering ovulation with a GnRH agonist instead of hCG; this GnRH agonist trigger markedly lowers the risk and severity of OHSS compared with an hCG trigger. In contrast, high-dose gonadotropins increase OHSS risk, prolonged bed rest has no proven protective effect, and avoiding GnRH antagonists would remove this protective control.

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