Which statement accurately describes minimal stimulation IVF?

• A. It uses high-dose gonadotropins.
• B. It reduces cost and risk and may yield similar outcomes in selected patients.
• C. It guarantees more eggs.
• D. It is no longer used.

Answer: (B)

Minimal stimulation IVF uses milder ovarian stimulation regimens, often with oral agents like letrozole or clomiphene and only low-dose injectable gonadotropins, to recruit fewer follicles. The aim is to lower cost, reduce the need for intensive monitoring, and minimize the risk of ovarian hyperstimulation syndrome, while still achieving similar pregnancy outcomes in carefully selected patients. That balance—less burden and risk with the possibility of comparable results in the right candidates—best describes minimal stimulation IVF. It does not focus on producing more eggs, is still in use today, and differs from high-dose stimulation used in conventional IVF.