Which statement best distinguishes embryo donation from donor gamete use in infertility treatment?

• A. Embryo donation uses embryos created with donor gametes by another couple
• B. Embryo donation uses only the recipient's own gametes
• C. Embryo donation ensures genetic relation to the intended parents
• D. Embryo donation is identical to donor egg therapy

Answer: (A)

The key distinction is the source and stage of genetic material: embryo donation uses an embryo that was created with donor gametes by another couple and then transferred to the recipient, whereas donor gamete use involves using donor eggs or donor sperm to create an embryo (often with the partner’s gamete). Because the embryo in embryo donation comes from donors, the resulting child is not genetically related to the recipient or the intended parents, which is why this option best captures the difference. The other statements don’t fit: embryo donation does not rely on the recipient’s own gametes; it does not guarantee genetic relation to the intended parents; and it is not identical to donor egg therapy, which uses donor eggs to create a new embryo.